---
title: Recherche et études
description: Les derniers résultats de la recherche et les innovations dans le domaine des céramiques de zircone et des implants dentaires. En savoir plus sur le rôle de premier plan de Z-SYSTEMS dans la recherche sur les implants en céramique.
---

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# Recherches et études

Les dernières découvertes et avancées dans la recherche sur les implants dentaires :  
Études et innovations actuelles sur la céramique et les implants dentaires en oxyde de Zircone.

#### First clinical results of dental screw implants made of zirconium oxide

[Mellinghoff J. Z Zahnärztl Impl 2006; 22(4): 288 (DE)](https://www.zsystems.com/hubfs/Erste%20klinische%20Ergebnisse%20zu%20dentalen%202006.pdf)

#### Zirconium dioxide implants – Practical experience: What are the aesthetic benefits of ceramic implants?

[Mellinghoff J. Implantologie 2014; 22(1): 51–60 (DE)](https://www.zsystems.com/hubfs/Zirkoniumdioxidimplantate%202014-1.pdf)

#### Role of immune Dysregulation in peri-implantitis

[Huang M., Wang C., Li P., Lu H., Li A., Xu S., Frontiers in Immunology 10.3389 1-17 (EN)](https://www.zsystems.com/hubfs/Role%20of%20immune%20dysregulation%20in%20peri-implantitis%202024.pdf)

#### Clinical and radiographic outcomes of zirconia dental implants

[Roehling S., Gahlert M., Bacevic M., Woelfler H., Laleman I. Clinical Oral Implants Res. 2023; 34(Suppl. 26): 112-124 (EN)](https://www.zsystems.com/hubfs/Clinical%20and%20radiographic%20outcomes%20of%20zirconia%20dental%20implants%202023.pdf)

#### Survival and success of zirconia compared with titanium implants

[Padhye N., Calcloarl E., Zuercher A., Tagliaferri S., Donos N., Clinical Oral Investigations 2023; (27) 6279-6290 (EN)](https://www.zsystems.com/hubfs/Survival%20and%20success%20of%20zirconia%20compared%20with%20titanium%20implants%202024.pdf)

#### Two-piece zirconia implants with two various platforms: RCCT’s preliminary results

[Oblak Č., Zarkovic Gjurin S., Hrovat P., Kobe T., Gašperšič R. CED-IADR, Oral Health Research Congress 2023, Abstract book, Nr. 0168, p. 91 (EN)](https://www.zsystems.com/hubfs/Two-Piece%20Zirconia%20Implants%20With%20Two%20Various%20Platforms_%20RCCTs%20Preliminary%20Results%20IADR%20Abstract%20Archives%20(1).pdf)

#### One-piece ceramic implants: A longitudinal study over a two-year observation period

[Mellinghoff J., Cacaci C., Detsch F. Implantologie 2015; 23(1): 89–100 (DE)](https://www.zsystems.com/hubfs/Einteilige%20Keramikimplantate%202014.pdf)

#### Clinical Outcomes of Zirconia implants: a systematic review and meta-Analysis

[Mohsen P., Soufi A., Chrcanovic B.R., Clinical Oral Investigations 2024; 1-12 (EN)](https://www.zsystems.com/hubfs/Clinical%20outcomes%20of%20zirconia%20implants%20a%20systematic%20review%202024.pdf)

#### Two-piece zirconia implants in the posterior mandible and maxilla: A cohort study with a follow-up period of 9 years

[Brunello G., Rauch N., Becker K., Hakimi A.R., Schwarz F., Becker J. Clin Oral Implants Res. 2022, 33(12), 1233 –1244 (EN)](https://www.zsystems.com/hubfs/Clinical%20Oral%20Implants%20Res%20-%202022%20-%20Brunello%20-%20Two%E2%80%90piece%20zirconia%20implants%20in%20the%20posterior%20mandible%20and%20maxilla%20%20A%20cohort%20(1).pdf)

#### Quality assessment of five randomly chosen ceramic oral implant systems: Cleanliness, surface topography, and clinical documentation

[Duddeck D.U., Albrektsson T., Wennerberg A., Larsson C., Mouhyi J., Beuer F. Int J Oral Maxillofac Implants 2021, 36(5), 863–874 (EN)](https://www.zsystems.com/hubfs/Quality%20Assessment%202020.pdf)

#### Titanium particles in peri-implantitis: distribution, pathogenesis and prospects

[Chen L., Tong Z., Luo H., Qu Y., Gu X., Si M., International Journal of Oral Science (2023); 1-13 (EN)](https://www.zsystems.com/hubfs/Titanium%20particles%20in%20peri-implantitis%202023.pdf)

#### Quality of the peri-implant soft tissue attachment of zirconia implants (-abutments): Comparison of the results of a literature review with the experiences of dental practitioners

[Mellinghoff J. Zahnärztl Impl 2010; 26(1): 62 (DE)](https://www.zsystems.com/hubfs/Qualit%C3%A4t%20des%20periimplant%C3%A4ren%20Weich%202010.pdf)

#### Fracture resistance of a bone-level two-piece zirconia oral implant system - the influence of artificial loading and hydrothermal aging

[Kohal R., Riesterer E., Vach K., Patzelt S., Ivekovic A., Einfalt L., Kocjan A., Hillebrecht A., J. Funct. Biomater 2024; 15(122) 1-16 (EN)](https://www.zsystems.com/hubfs/Fracture%20Resistance%20of%20a%20Bone-Level%202024.pdf)

#### Influence of multiple used implant drills on their cutting performance and fracture resistance

[Alevizakos V., Mosch R., von See C. Materials 2023, 16(15), 5271 (EN)](https://www.zsystems.com/hubfs/materials-16-05271%20(1).pdf)

#### Ligature-induced peri-implant bone loss around loaded zirconia and titanium implants

[Roehling St., Gahlert M., Janner S., Meng B., Woelfler H., Cochran D.L. Int J Oral Maxillofac Implants. 2019, 34(2), 357–36 (EN)](https://www.zsystems.com/hubfs/Ligature%20induced%202018.pdf)

#### Immune dysregulation and macrophage polarization in peri-implantitis

[Li Y., Li X., Guo D., Meng L., Feng X., Zhang Y., Pan S., Frontiers in Bioengineering and Biotechnology 2024; 10(3389) 1-14 (EN)](https://www.zsystems.com/hubfs/Immune%20dysregulation%20and%20macrophage%20polarization%20in%20peri-implantitis%202024.pdf)

#### Is there a better biomaterial for dental implants than titanium? – A review and meta-study analysis

[Haugen H.J., Chen H. Funct Biomater. 2022, 13(2), 46 (EN)](https://www.zsystems.com/hubfs/jfb-13-00046-v2%20(1).pdf)

#### The systemic and local interactions related to titanium implant corrosion and hypersensitivity reactions: a narrative review of the literature

[Swalsky A., Noumbissi S., Wiedemann T., International Journal of Implant Dentistry (2024) 1-10 (EN)](https://www.zsystems.com/hubfs/The%20systemic%20and%20local%20interactions%202024.pdf)

#### Osseointegration of zirconia implants with different surface characteristics: an evaluation in rabbits

[Hoffmann O., Angelov N., Zafiropoulos GG., Andreana S. Int J Oral Maxillofac Implants 2012; 27(2): 352–358 (EN)](https://www.zsystems.com/hubfs/Osseointegration%20of%20Zirconia%20implant%202012.pdf)

#### Stability assessment of 85 standblasted and laser-etched surface zirconia implant using the periotest method over 4 months of bone integration time

[Noumbissi S., Piconi C. Key Engineering Materials 2016, Vol. 720; 65–68 (EN)](https://www.zsystems.com/hubfs/Stability%20Assessment%20of%2085%20Sandblasted%20and%20Laser-Etched%20Surface%20Zirconia%20Implant%202016.pdf)

#### Titanium allergy caused by dental implants: A systematic literature review and case report

[Poli P.P., de Miranda F.V., Polo T.O.B., Santiago Júnior J.F., Lima Neto T.J., Rios B.R., Assunção W.G., Ervolino E., Maiorana C., Faverani., L.P. Materials 2021, 14(18), 5239 (EN)](https://www.zsystems.com/hubfs/Titanium%20Allergy%20Caused%20by%20Dental%20Implants_%20A%20Systematic%20Literature%20Review%20and%20Case%20Report.pdf)

#### Histologic osseointegration level comparing titanium and zirconia dental implants: Meta-analysis of preclinical studies

[da Silva Remísio M.J., Borges T., Castro F., Alexandre Gehrke S., Hasse Fernandes J.C., Vicentis de Oliveira Fernandes G. Int J Oral Maxillofac Implants 2023, 38(4), 667–680 (EN)](https://www.zsystems.com/hubfs/Histologic%20Osseointegration%20Level%20Comparing%20Titanium%20and%202022.pdf)

#### One-piece versus two-piece ceramic dental implants

[Bollen C., Hakobayan G., Jörgens M., British Dental Journal 2024; (236) 383-387 (EN)](https://www.zsystems.com/hubfs/One-piece%20versus%20two-piece%20ceramic%20dental%20implants%202024.pdf)

#### Radioactive potential of zirconium-dioxide used for dental applications

[Bavbek A., Özcan M., Eskitascioglu G., J. Appl. Biomater Funct Mater 2014; 12(1): 35-40](https://www.zsystems.com/hubfs/Radioactive%20potential%20of%20zirconium-dioxide%20used%20for%20dental%202014%20(1).pdf)

#### Two-year outcomes of tissue-level and bone-level two-piece zirconia implants: a case series

[Žarković Gjurin S., Povšič K., Kobe T., Žužek B., Gašperšič R., Oblak Č. Oral. 2026; 6(1):1 (EN)](https://www.zsystems.com/hubfs/Two-Year%20Outcomes%20of%20Tissue-Level%20and%20Bone-Level%20Two-Piece%20Zirconia%20Implants.pdf)

#### Multivariate analysis of the survival rates and risk factors of one-piece zirconia implants supporting single crowns or fixed dental prostheses: A retrospective cohort study with follow-up periods of up to 8 Years

[Cortés-Bretón Brinkmann J., Bazal-Bonelli S., Suárez MJ., Meniz-García C., Madrigal Martìnez-Pereda C., López-Quiles J. Dentistry Journal. 2026; 14(5):282 (EN)](https://www.zsystems.com/hubfs/Multivariate%20Analysis%20of%20the%20Survival%20Rates%20and%20Risk%20Factors%20of%20One-Piece%20Zirconia%20Implants%20Supporting%20Single%20Crowns%20or%20Fixed%20Dental%20Prostheses.pdf)

#### Long-term clinical and radiographic outcomes of ceramic dental implants: An 11-year retrospective cohort study

[Monzavi M., Masnavi M., Zraiqat A., Manesh A. J Esthet Restor Dent. 2026 (EN)](https://www.zsystems.com/hubfs/J%20Esthet%20Restor%20Dent%20-%202026%20-%20Monzavi%20-%20Long%E2%80%90Term%20Clinical%20and%20Radiographic%20Outcomes%20of%20Ceramic%20Dental%20Implants%20%20An%2011%E2%80%90Year%20(1).pdf)

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